EMG1 antibody (N-Term)

Catalog No. ABIN2778974

The Rabbit Polyclonal anti-EMG1 antibody has been validated for WB and IHC. It is suitable to detect EMG1 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for EMG1 antibody (N-Term) (ABIN2778974)

Target: EMG1 (EMG1 Nucleolar Protein Homolog (EMG1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EMG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-EMG1 Antibody

Binding Specificity: N-Term

Sequence: SLETVKVGKT YELLNCDKHK SILLKNGRDP GEARPDITHQ SLLMLMDSPL

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against EMG1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EMG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 244 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-EMG1 antibody (ABIN2778974)

Armistead, Khatkar, Meyer, Mark, Patel, Coghlan, Lamont, Liu, Wiechert, Cattini, Koetter, Wrogemann, Greenberg, Entian, Zelinski, Triggs-Raine: "Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome." in: American journal of human genetics, Vol. 84, Issue 6, pp. 728-39, (2009) (PubMed).

Target Details for EMG1

Target: EMG1 (EMG1 Nucleolar Protein Homolog (EMG1))

Alternative Name: EMG1

Background: EMG1 involved in 40S ribosomal subunit biogenesis. It seems to play a role a methylation reaction in pre-rRNA processing.
Alias Symbols: C2F, NEP1, Grcc2f
Protein Interaction Partner: FAM74A4, UBC, RPA3, RPA2, RPA1, EED, rev, HECW2, IL7R, FN1, BYSL, APP, NEDD8, SLC25A38, NAT6, PSMB7, KHDRBS1, PSME1, HIVEP1, CTSE, ANXA3,
Protein Size: 244

Molecular Weight: 27 kDa

Gene ID: 10436

NCBI Accession: NM_006331, NP_006322

UniProt: Q92979