PRP6/ANT-1 antibody (N-Term)
Quick Overview for PRP6/ANT-1 antibody (N-Term) (ABIN2779038)
Target
See all PRP6/ANT-1 (PRPF6) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- PGKRTVGDQM KKNQAADDDD EDLNDTNYDE FNGYAGSLFS SGPYEKDDEE
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Characteristics
- This is a rabbit polyclonal antibody against PRPF6. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PRPF6
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 941 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PRP6/ANT-1 (PRPF6) (PRP6 Pre-mRNA Processing Factor 6 Homolog (PRPF6))
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Alternative Name
- PRPF6
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Background
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PRPF6 appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. PRPF6 also can bind androgen receptor, providing a link between transcriptional activation and splicing.The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.
Alias Symbols: ANT-1, TOM, ANT1, Prp6, hPrp6, U5-102K, C20orf14
Protein Interaction Partner: SUMO2, SUMO3, UBC, MDM2, PASK, RPA3, RPA2, RPA1, EED, rev, PARK2, PRPF4B, UBD, HDAC11, CTNNB1, MMS19, MYC, IK, PRPF31, SRRM2, CD2BP2, WHSC1, NOTCH1, ZNF326, TRA2A, PRPF19, SF3B3, NCSTN, SNRNP200, ACIN1, U2AF2, SUPT16H, PRPF8, RBM14, SAP18, THRAP3, EIF4A3,
Protein Size: 941 -
Molecular Weight
- 104 kDa
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Gene ID
- 24148
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NCBI Accession
- NM_012469, NP_036601
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UniProt
- O94906
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Proton Transport, Dicarboxylic Acid Transport
Target
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