EXOSC7 antibody (N-Term)

Catalog No. ABIN2779075

This Rabbit Polyclonal antibody specifically detects EXOSC7 in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Horse, Guinea Pig, Rabbit and Pig.

Quick Overview for EXOSC7 antibody (N-Term) (ABIN2779075)

Target: EXOSC7 (Exosome Component 7 (EXOSC7))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-EXOSC7 Antibody

Binding Specificity: N-Term

Sequence: EVETDVVSNT SGSARVKLGH TDILVGVKAE MGTPKLEKPN EGYLEFFVDC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against EXOSC7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 291 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EXOSC7

Target: EXOSC7 (Exosome Component 7 (EXOSC7))

Alternative Name: EXOSC7

Background: EXOSC7 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. The protein is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA.
Alias Symbols: EAP1, FLJ26543, KIAA0116, RRP42, Rrp42p, hRrp42p, p8
Protein Interaction Partner: TP53, UBC, RPA3, RPA2, RPA1, rev, HECW2, EXOSC6, EXOSC2, EXOSC10, DXO, AICDA, EXOSC4, APP, DIS3L, EXOSC3, DIS3, EXOSC1, EXOSC5, SKIV2L2, MPP6, EXOSC8, IP6K1, EXOSC9,
Protein Size: 291

Molecular Weight: 32 kDa

Gene ID: 23016

NCBI Accession: NM_015004, NP_055819

UniProt: B2RDZ9