PUM2 antibody (N-Term)

Catalog No. ABIN2779083

The Rabbit Polyclonal anti-PUM2 antibody (ABIN2779083) specifically detects PUM2 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio) samples.

Quick Overview for PUM2 antibody (N-Term) (ABIN2779083)

Target: PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PUM2 Antibody

Binding Specificity: N-Term

Sequence: MNHDFQALAL ESRGMGELLP TKKFWEPDDS TKDGQKGIFL GDDEWRETAW

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against PUM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PUM2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1064 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PUM2

Target: PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))

Alternative Name: PUM2

Background: PUM2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.
Alias Symbols: FLJ36528, KIAA0235, MGC138251, MGC138253, PUMH2, PUML2
Protein Interaction Partner: NANOS3, BMI1, gag-pol, UBC, DAZL, DAZ1, ELAVL1, MED4, AURKA, NANOS1, DAZ2, DAZ4, PUM2, MED23, IKZF5,
Protein Size: 1064

Molecular Weight: 114 kDa

Gene ID: 23369

NCBI Accession: NM_015317, NP_056132

UniProt: B3KSL0

Pathways: Ribonucleoprotein Complex Subunit Organization