PUM2 antibody (N-Term)
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- Target See all PUM2 Antibodies
- PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PUM2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MNHDFQALAL ESRGMGELLP TKKFWEPDDS TKDGQKGIFL GDDEWRETAW
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against PUM2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PUM2
- Top Product
- Discover our top product PUM2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1064 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))
- Alternative Name
- PUM2 (PUM2 Products)
- Background
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PUM2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.
Alias Symbols: FLJ36528, KIAA0235, MGC138251, MGC138253, PUMH2, PUML2
Protein Interaction Partner: NANOS3, BMI1, gag-pol, UBC, DAZL, DAZ1, ELAVL1, MED4, AURKA, NANOS1, DAZ2, DAZ4, PUM2, MED23, IKZF5,
Protein Size: 1064 - Molecular Weight
- 114 kDa
- Gene ID
- 23369
- NCBI Accession
- NM_015317, NP_056132
- UniProt
- B3KSL0
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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