CPSF3 antibody (N-Term)

Catalog No. ABIN2779099

This Rabbit Polyclonal antibody specifically detects CPSF3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for CPSF3 antibody (N-Term) (ABIN2779099)

Target: CPSF3 (Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPSF3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CPSF3 Antibody

Binding Specificity: N-Term

Sequence: MAAEIPNIKP DILIIESTYG THIHEKREER EARFCNTVHD IVNRGGRGLI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CPSF3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CPSF3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 684 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CPSF3

Target: CPSF3 (Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3))

Alternative Name: CPSF3

Background: CPSF3 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF3 subfamily. It is component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.
Alias Symbols: CPSF, YSH1, CPSF73, CPSF-73
Protein Interaction Partner: UBC, SUMO1, WWOX, AICDA, POLR2A, NPM1, TUT1, SYMPK, CSTF2, CPSF2, PAXIP1, MDC1, BARD1, FIP1L1, POLR1E, WDR33, CPSF1, UBD, SIRT7, SMARCAD1, RRAGA, TBP, CDC73, CLP1, PAPOLA, YWHAG,
Protein Size: 684

Molecular Weight: 75 kDa

Gene ID: 51692

NCBI Accession: NM_016207, NP_057291

UniProt: Q9UKF6