CELF4 antibody (Middle Region)

Catalog No. ABIN2779151

This Rabbit Polyclonal antibody specifically detects CELF4 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Pig, Rabbit and Zebrafish (Danio rerio)and has been mentioned in 1 publication.

Quick Overview for CELF4 antibody (Middle Region) (ABIN2779151)

Target: CELF4 (CUGBP, Elav-Like Family Member 4 (CELF4))

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CELF4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CELF4 Antibody

Binding Specificity: Middle Region

Sequence: PMAAFAAAQM QQMAALNMNG LAAAPMTPTS GGSTPPGITA PAVPSIPSPI

Predicted Reactivity: Cow: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against BRUNOL4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BRUNOL4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 486 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CELF4 antibody (ABIN2779151)

Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns." in: Genome biology, Vol. 8, Issue 8, pp. R154, (2008) (PubMed).

Target Details for CELF4

Target: CELF4 (CUGBP, Elav-Like Family Member 4 (CELF4))

Alternative Name: BRUNOL4

Background: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mR
Alias Symbols: BRUNOL-4, CELF4, BRUNOL4
Protein Interaction Partner: APP, LYST,
Protein Size: 486

Molecular Weight: 52 kDa

Gene ID: 56853

NCBI Accession: NM_020180, NP_064565

UniProt: Q9BZC1

Pathways: Ribonucleoprotein Complex Subunit Organization, Synaptic Membrane