CBX4 antibody (N-Term)

Catalog No. ABIN2779230

This anti-CBX4 antibody is a Rabbit Polyclonal antibody detecting CBX4 in WB and IHC. Suitable for Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit and Zebrafish (Danio rerio). This Primary Antibody has been cited in 1 publication.

Quick Overview for CBX4 antibody (N-Term) (ABIN2779230)

Target: CBX4 (Chromobox Homolog 4 (CBX4))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CBX4 Antibody

Binding Specificity: N-Term

Sequence: LLIAFQNRER QEQLMGYRKR GPKPKPLVVQ VPTFARRSNV LTGLQDSSTD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against CBX4. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CBX4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 560 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CBX4 antibody (ABIN2779230)

Hao, Midic, Garriga, Latham: "Contribution of CBX4 to cumulus oophorus cell phenotype in mice and attendant effects in cumulus cell cloned embryos." in: Physiological genomics, Vol. 46, Issue 2, pp. 66-80, (2014) (PubMed).

Target Details for CBX4

Target: CBX4 (Chromobox Homolog 4 (CBX4))

Alternative Name: CBX4

Background: The polycomb group (PcG) protein HPC2, which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. Pc2 dramatically enhances CtBP sumoylation. Pc2 is a SUMO E3, and Polycomb Group bodies may be sumoylation centers.
Alias Symbols: PC2, NBP16
Protein Interaction Partner: Rnf111, SUMO1, NEDD8, CBS, BMI1, EED, RNF2, HECW2, SOX2, YWHAE, YWHAB, CCDC158, DIS3L2, HIST4H4, CBX2, PARP12, RNF213, ZKSCAN7, DCAF6, KDM3A, MYCBP2, ANKRD26, PSME3, TRANK1, CBX4, HIST1H2AB, YWHAZ, SKIL, NPM1, HIST1H2BB, GTF2I, PHC2, CSNK2B, CSNK2A2, CSNK
Protein Size: 560

Molecular Weight: 61 kDa

Gene ID: 8535

NCBI Accession: NM_003655, NP_003646