L3MBTL2 antibody (N-Term)

Catalog No. ABIN2779267

The Rabbit Polyclonal anti-L3MBTL2 antibody has been validated for WB. It is suitable to detect L3MBTL2 in samples from Human, Rat, Mouse, Dog, Cow, Horse, Guinea Pig, Rabbit and Pig.

Quick Overview for L3MBTL2 antibody (N-Term) (ABIN2779267)

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This L3MBTL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-L3MBTL2 Antibody

Binding Specificity: N-Term

Sequence: DSFRSYNSSV GSESSSYLEE SSEAENEDRE AGELPTSPLH LLSPGTPRSL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against L3MBTL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human L3MBTL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 614 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for L3MBTL2

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Alternative Name: L3MBTL2

Background: L3MBTL2 contains 1 FCS-type zinc finger and 4 MBT repeats. It is putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.
Alias Symbols: H-l(3)mbt-l, L3MBT
Protein Interaction Partner: TRIM42, STAC3, PHF10, TBC1D9B, PAICS, AES, SUMO2, SUMO1, PIAS1, HIST1H4A, HIST1H3A, RNF2, MPP3, PCGF6, RYBP, YAF2, SMARCAD1, HIST4H4, CBX3, HIST3H3, E2F6, Lin54, HDAC3, MEAF6, STAM2, RB1,
Protein Size: 614

Molecular Weight: 69 kDa

Gene ID: 83746

NCBI Accession: NM_001003689, NP_001003689