HSP90AA1 antibody (N-Term)

Catalog No. ABIN2779296

The Rabbit Polyclonal anti-HSP90AA1 antibody has been validated for WB and IHC. It is suitable to detect HSP90AA1 in samples from Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Sheep and Horse.

Quick Overview for HSP90AA1 antibody (N-Term) (ABIN2779296)

Target: HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Sheep, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP90AA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HSP90AA1 Antibody

Binding Specificity: N-Term

Sequence: HLYKDLQPFI LLRLLMPEET QTQDQPMEEE EVETFAFQAE IAQLMSLIIN

Predicted Reactivity: Cow: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%

Characteristics: This is a rabbit polyclonal antibody against HSP90AA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HSP90AA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 854 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HSP90AA1

Target: HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))

Alternative Name: HSP90AA1

Background: HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1, MIM 191175) and mitochondria (TRAP1, MIM 606219).
Alias Symbols: FLJ31884, HSP86, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, HSP89A
Protein Interaction Partner: AHSA1, STUB1, HUWE1, ISG15, RAF1, PTGDS, PTGDR, SIRT1, CDC37, STIP1, HSF1, HIF1A, NR3C1, UBC, PTGES3, FUS, CDC25C, CDK1, SUMO1, STK36, KEAP1, PSMD10, AURKA, SUMO2, SUMO3, MAP3K11, MDM2, LGALS3BP, CEP57, AURKB, CEP76, VHL, TUBG1, TP53, BRCA1, CEP250, AIP,
Protein Size: 854

Molecular Weight: 98 kDa

Gene ID: 3320

NCBI Accession: NM_001017963, NP_001017963

UniProt: P07900

Pathways: M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals