ARNTL antibody (N-Term)

Catalog No. ABIN2779410

The Rabbit Polyclonal anti-ARNTL antibody has been validated for WB and IHC. It is suitable to detect ARNTL in samples from Human, Rat, Mouse, Cow, Dog, Sheep, Rabbit, Horse and Guinea Pig.

Quick Overview for ARNTL antibody (N-Term) (ABIN2779410)

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Reactivity: Human, Rat, Mouse, Cow, Dog, Sheep, Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARNTL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ARNTL Antibody

Binding Specificity: N-Term

Sequence: TDYQESMDTD KDDPHGRLEY TEHQGRIKNA REAHSQIEKR RRDKMNSF

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against ARNTL. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ARNTL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 625 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARNTL

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Alternative Name: ARNTL

Background: ARNTL is a general dimerization partner for a subset of the basic-helix-loop-helix (bHLH)-PER-ARNT-SIM (PAS) superfamily of transcriptional regulators.
Alias Symbols: TIC, JAP3, MOP3, BMAL1, PASD3, BMAL1c, bHLHe5
Protein Interaction Partner: HIF1A, NPAS2, UBE3A, UBC, DYRK1B, CLOCK, Cry2, SIRT1, BHLHE40, NPAS4, PER3, CRY1, EPAS1, CSNK1E, AHR, HLF, HSP90AA1, SUMO2, SUMO3, RXRA, RARA, KAT2B, EP300,
Protein Size: 625

Molecular Weight: 25 kDa

Gene ID: 406

NCBI Accession: NM_015642, NP_001169

Pathways: Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effect