MYEF2 antibody (N-Term)

Catalog No. ABIN2779445

The Rabbit Polyclonal anti-MYEF2 antibody is suitable to detect MYEF2 in samples from Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig and Rabbit. It has been validated for WB.

Quick Overview for MYEF2 antibody (N-Term) (ABIN2779445)

Target: MYEF2 (Myelin Expression Factor 2 (MYEF2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYEF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MYEF2 Antibody

Binding Specificity: N-Term

Sequence: PAEAEKQQPQ HSSSSNGVKM ENDESAKEEK SDLKEKSTGS KKANRFHPYS

Predicted Reactivity: Cow: 86%, Dog: 77%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against MYEF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MYEF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 600 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYEF2

Target: MYEF2 (Myelin Expression Factor 2 (MYEF2))

Alternative Name: MYEF2

Background: MYEF2 is the transcriptional repressor of the myelin basic protein gene (MBP). MYEF2 binds to the proximal MB1 element 5'-TTGTCC-3' of the MBP promoter. Its binding to MB1 and function are inhibited by PURA.
Alias Symbols: FLJ11213, HsT18564, KIAA1341, MEF-2, MGC87325, MST156, MSTP156
Protein Interaction Partner: COG8, TEX11, TRAF1, GOLGA2, UBC, EED, RNF2, BMI1, SOX2, CDK19, SIRT7, TADA2A, ATXN1, PPARGC1A, HDAC5, MAPK14, tat, SMARCA4,
Protein Size: 600

Molecular Weight: 64 kDa

Gene ID: 50804

NCBI Accession: NM_016132, NP_057216

UniProt: Q9P2K5