FOXF1 antibody (C-Term)

Catalog No. ABIN2779550

This Rabbit Polyclonal antibody specifically detects FOXF1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Horse, Rat, Cow, Guinea Pig, Rabbit and Dog and has been mentioned in 2+ publications.

Quick Overview for FOXF1 antibody (C-Term) (ABIN2779550)

Target: FOXF1 (Forkhead Box F1 (FOXF1))

Reactivity: Human, Mouse, Horse, Rat, Cow, Guinea Pig, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FOXF1 Antibody

Binding Specificity: C-Term

Sequence: PCNPAANPLS GSLSTHSLEQ PYLHQNSHNA PAELQGIPRY HSQSPSMCDR

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against FOXF1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FOXF1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 354 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FOXF1 antibody (ABIN2779550)

Tamura, Sasaki, Koyama, Takeda, Idogawa, Tokino: "Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness." in: Oncogene, Vol. 33, Issue 40, pp. 4837-46, (2014) (PubMed).

Lo, Lee, Chen, Reisman, Berger, Sukumar: "Cytoplasmic mislocalization of overexpressed FOXF1 is associated with the malignancy and metastasis of colorectal adenocarcinomas." in: Experimental and molecular pathology, Vol. 94, Issue 1, pp. 262-9, (2013) (PubMed).

Target Details for FOXF1

Target: FOXF1 (Forkhead Box F1 (FOXF1))

Alternative Name: FOXF1

Background: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined, however, it may play a role in the regulation of pulmonary genes as well as embryonic development.
Alias Symbols: FKHL5, ACDMPV, FREAC1
Protein Size: 354

Molecular Weight: 38 kDa

Gene ID: 2294

NCBI Accession: NM_001451, NP_001442

UniProt: Q12946

Pathways: Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process