FOXC1 antibody (C-Term)

Catalog No. ABIN2779552

The Rabbit Polyclonal anti-FOXC1 antibody has been validated for WB. It is suitable to detect FOXC1 in samples from Human, Mouse and Rat.

Quick Overview for FOXC1 antibody (C-Term) (ABIN2779552)

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FOXC1 Antibody

Binding Specificity: C-Term

Sequence: GERGGHLQGA PGGAGGSAVD NPLPDYSLPP VTSSSSSSLS HGGGGGGGGG

Predicted Reactivity: Human: 93%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against FOXC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FOXC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 553 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FOXC1

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Alternative Name: FOXC1

Background: FOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined, however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.
Alias Symbols: ARA, IGDA, IHG1, FKHL7, IRID1, RIEG3, FREAC3, FREAC-3
Protein Interaction Partner: SOX2, gag-pol, ELAVL1, SUMO2, UBC, HMGB1,
Protein Size: 553

Molecular Weight: 57 kDa

Gene ID: 2296

NCBI Accession: NM_001453, NP_001444

UniProt: Q12948

Pathways: Chromatin Binding, Glycosaminoglycan Metabolic Process