EYA3 antibody (Middle Region)

Catalog No. ABIN2779571

The Rabbit Polyclonal anti-EYA3 antibody (ABIN2779571) specifically detects EYA3 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Horse, Sheep and Dog samples.

Quick Overview for EYA3 antibody (Middle Region) (ABIN2779571)

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Horse, Sheep, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EYA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-EYA3 Antibody

Binding Specificity: Middle Region

Sequence: QSRKNMTSKN RGKRKADATS SQDSELERVF LWDLDETIII FHSLLTGSYA

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Sheep: 92%

Characteristics: This is a rabbit polyclonal antibody against EYA3. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EYA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 573 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EYA3

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Alternative Name: EYA3

Background: Eyes absent homolog 3 (EYA3) is a member of the eyes absent (EYA) family of proteins. This protein may act as a transcriptional activator and have a role during development. A similar protein in mice can act as a transcriptional activator. Two transcript variants encoding distinct isoforms have been identified for this gene.
Protein Interaction Partner: UBC, SKI, H2AFX, DACH1, SIX5, SIX4, SIX2, SIX1,
Protein Size: 573

Molecular Weight: 63 kDa

Gene ID: 2140

NCBI Accession: NM_001990, NP_001981

UniProt: Q99504

Pathways: Positive Regulation of Response to DNA Damage Stimulus