LHX3 antibody (Middle Region)

Catalog No. ABIN2779647

The Rabbit Polyclonal anti-LHX3 antibody (ABIN2779647) specifically detects LHX3 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Cow, Zebrafish (Danio rerio), Guinea Pig and Goat samples.

Quick Overview for LHX3 antibody (Middle Region) (ABIN2779647)

Target: LHX3 (LIM Homeobox 3 (LHX3))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Zebrafish (Danio rerio), Guinea Pig, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LHX3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LHX3 Antibody

Binding Specificity: Middle Region

Sequence: PSGAPGGPPP MRVLAGNGPS SDLSTGSSGG YPDFPASPAS WLDEVDHAQF

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against LHX3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LHX3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 402 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LHX3

Target: LHX3 (LIM Homeobox 3 (LHX3))

Alternative Name: LHX3

Background: LHX3 encodes a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. This gene encodes a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. Two transcripts variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: DKFZp762A2013, M2-LHX3, LIM3, CPHD3
Protein Interaction Partner: ISL2, IFT172, LDB1, CITED2, ISL1, RLIM, LMX1A, LHX1,
Protein Size: 402

Molecular Weight: 44 kDa

Gene ID: 8022

NCBI Accession: NM_014564, NP_055379

UniProt: Q5TB40