CTBP1 antibody (N-Term)

Catalog No. ABIN2779663

The Rabbit Polyclonal anti-CTBP1 antibody has been validated for WB and IHC. It is suitable to detect CTBP1 in samples from Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Horse, Cow, Guinea Pig and Rabbit.

Quick Overview for CTBP1 antibody (N-Term) (ABIN2779663)

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Horse, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CTBP1 Antibody

Binding Specificity: N-Term

Sequence: TREDLEKFKA LRIIVRIGSG FDNIDIKSAG DLGIAVCNVP AASVEETADS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 75%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CTBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CTBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 429 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CTBP1

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Alternative Name: CTBP1

Background: CTBP1 binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
Alias Symbols: BARS, MGC104684
Protein Interaction Partner: CTBP2, CTBP1, CRY2, NOL4L, FOXP2, DMRTB1, TSHZ3, BCAS3, PLCB1, CEP68, KLF12, IKZF1, NOL4, TGIF1, MAPK9, PRKAA1, HOXB5, TCF4, SNRPN, DGCR6, NRIP1, FUNDC1, LNX1, LCOR, RNF111, KLF3, IKZF2, RAI2, ZBTB18, ARNT2, ZEB2, PIAS2, CDC23, LCORL, MARCH10, SMAD6, UBC,
Protein Size: 429

Molecular Weight: 46 kDa

Gene ID: 1487

NCBI Accession: NM_001012614, NP_001012632

UniProt: Q7Z2Q5

Pathways: Retinoic Acid Receptor Signaling Pathway