CTBP1 antibody (C-Term)

Catalog No. ABIN2779661

Cited in 1 publication. The Rabbit Polyclonal anti-CTBP1 antibody (ABIN2779661) specifically detects CTBP1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Pig, Dog and Horse samples.

Quick Overview for CTBP1 antibody (C-Term) (ABIN2779661)

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Reactivity: Human, Mouse, Rat, Pig, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CTBP1 Antibody

Binding Specificity: C-Term

Purpose: CTBP1 Antibody - C-terminal region

Sequence: TGIPAAVEGI VPSAMSLSHG LPPVAHPPHA PSPGQTVKPE ADRDHASDQL

Predicted Reactivity: Dog: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CTBP1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CTBP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8095815

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-CTBP1 antibody (ABIN2779661)

Mittal, Singh, Misra, Chaudhuri: "SLUG-induced elevation of D1 cyclin in breast cancer cells through the inhibition of its ubiquitination." in: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 469-79, (2011) (PubMed).

Target Details for CTBP1

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Alternative Name: CTBP1

Background:

Background Information: The phosphoprotein C-terminal binding protein 1 (CTBP-1) binds the C-terminus of adenovirus E1A protein. CTBP-1 is a transcriptional repressor and may play a role during cellular proliferation. A second closely related gene, CTBP2, maps to chromosome 21.

Gene Name: C-terminal binding protein 1

Alternative Symbols: BARS, HADDTS

Protein Name: C-terminal-binding protein 1

Molecular Weight: 48kDa

Gene ID: 1487

NCBI Accession: NP_001319

UniProt: Q13363

Pathways: Retinoic Acid Receptor Signaling Pathway