CBX5 antibody (Middle Region)

Catalog No. ABIN2779672

The Rabbit Polyclonal anti-CBX5 antibody has been validated for WB and IHC. It is suitable to detect CBX5 in samples from Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Horse and Sheep.

Quick Overview for CBX5 antibody (Middle Region) (ABIN2779672)

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CBX5 Antibody

Binding Specificity: Middle Region

Sequence: KYKKMKEGEN NKPREKSESN KRKSNFSNSA DDIKSKKKRE QSNDIARGFE

Predicted Reactivity: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against CBX5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CBX5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 191 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CBX5

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Alternative Name: CBX5

Background: CBX5 is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing.
Alias Symbols: HP1, HP1A
Protein Interaction Partner: SUV39H1, SP100, SUV39H2, WHSC1L1, VPS28, GOLGA8EP, SENP7, TRIM28, HIST3H3, RARA, UBC, ZBTB16, MDM2, XRN1, SRPK2, SRPK1, PRR14, EHMT2, MCC, TCEB1, TRIM39, BGLAP, BCL7A, ACTL6A, MIS12, ZNF747, ZNF649, WIZ, ZNF462, ZNF302, LRIF1, CDCA8, ZNF280D, AHDC1, NARF,
Protein Size: 191

Molecular Weight: 22 kDa

Gene ID: 23468

NCBI Accession: NM_012117, NP_036249

UniProt: P45973