GATA3 antibody (C-Term)

Catalog No. ABIN2779713

This Rabbit Polyclonal antibody specifically detects GATA3 in WB, IHC and IF. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse and Sheepand has been mentioned in 1 publication.

Quick Overview for GATA3 antibody (C-Term) (ABIN2779713)

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GATA3 Antibody

Binding Specificity: C-Term

Sequence: RNRKMSSKSK KCKKVHDSLE DFPKNSSFNP AALSRHMSSL SHISPFSHSS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against GATA3. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GATA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 443 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GATA3 antibody (ABIN2779713)

Kaminuma, Kitamura, Kitamura, Miyagishi, Taira, Yamamoto, Miura, Miyatake: "GATA-3 suppresses IFN-gamma promoter activity independently of binding to cis-regulatory elements." in: FEBS letters, Vol. 570, Issue 1-3, pp. 63-8, (2004) (PubMed).

Target Details for GATA3

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Alternative Name: GATA3

Background: Trans-acting T-cell specific transcription factor GATA-3 is a member of GATA family of transcription factors that regulates development of multiple tissues. It is an important transcription factor in regulating human Th2 cell differentiation in vivo.
Alias Symbols: HDR, HDRS
Protein Interaction Partner: PSMA3, FOXP3, USP21, UBC, SPI1, BRCA1, MYB, REPIN1, SP1, TBX21, HDAC5, HDAC4, HDAC3, RARB, MDM2, BMI1, MED1, ZFPM2, SATB1, TAL1, LMO1, LMO2, ETS2, ETS1,
Protein Size: 443

Molecular Weight: 48 kDa

Gene ID: 2625

NCBI Accession: NM_002051, NP_002042

UniProt: P23771

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation