HBP1 antibody (Middle Region)

Catalog No. ABIN2779721

This Rabbit Polyclonal antibody specifically detects HBP1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for HBP1 antibody (Middle Region) (ABIN2779721)

Target: HBP1 (HMG Box-Containing Protein 1 (HBP1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HBP1 Antibody

Binding Specificity: Middle Region

Sequence: FSKNCGSPGS SQLSSNSLYA KAVKNHSSGT VSATSPNKCK RPMNAFMLFA

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against HBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 514 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HBP1

Target: HBP1 (HMG Box-Containing Protein 1 (HBP1))

Alternative Name: HBP1

Background: HBP1 is a transcriptional repressor that binds to the promoter region of target genes. It plays a role in the regulation of the cell cycle and of the Wnt pathway. HBP1 binds preferentially to the sequence 5'-TTCATTCATTCA-3'.The protein also disrupts the interaction between DNA and TCF4.
Alias Symbols: FLJ16340
Protein Interaction Partner: FBXW11, UBC, TMEM37, SMAD1, ZNF212, KIAA1279, EWSR1, CD2AP, EP300, CREBBP, MYC, ANKRD2, SIN3A, SAP30, TCF4, HDAC1, RBL2, RB1,
Protein Size: 514

Molecular Weight: 58 kDa

Gene ID: 26959

NCBI Accession: NM_012257, NP_036389

UniProt: O60381