Ceramide Synthase 2 antibody (N-Term)

Catalog No. ABIN2779748

This Rabbit Polyclonal antibody specifically detects Ceramide Synthase 2 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Guinea Pig, Dog and Rabbit.

Quick Overview for Ceramide Synthase 2 antibody (N-Term) (ABIN2779748)

Target: Ceramide Synthase 2 (CERS2)

Reactivity: Human, Mouse, Rat, Cow, Horse, Guinea Pig, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ceramide Synthase 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Ceramide Synthase 2 Antibody

Binding Specificity: N-Term

Sequence: EKTRLRAPPN ATLEHFYLTS GKQPKQVEVE LLSRQSGLSG RQVERWFRRR

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against LASS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LASS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 380 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Ceramide Synthase 2

Target: Ceramide Synthase 2 (CERS2)

Alternative Name: LASS2

Background: LASS2 is a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.
Alias Symbols: CerS2, FLJ10243, L3, MGC987, SP260, TMSG1, LASS2
Protein Interaction Partner: HSP90AA1, ELOVL3, ELOVL7, ELOVL6, ELOVL1, ELOVL5, ELOVL2, HSD17B12, TECR, ELOVL4, vpu, SLC39A1, SLC19A2, UBC, TMBIM6, SLC22A1, PEX6, ATP6V0C, ASGR2, ASGR1, FLOT1, FUBP1, NDN,
Protein Size: 380

Molecular Weight: 45 kDa

Gene ID: 29956

NCBI Accession: NM_022075, NP_071358

UniProt: Q96G23