NR4A1 antibody (C-Term)

Catalog No. ABIN2779759

This Rabbit Polyclonal antibody specifically detects NR4A1 in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for NR4A1 antibody (C-Term) (ABIN2779759)

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR4A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NR4A1 Antibody

Binding Specificity: C-Term

Sequence: RGRLPSKPKQ PPDASPANLL TSLVRAHLDS GPSTAKLDYS KFQELVLPHF

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against NR4A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NR4A1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 598 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NR4A1

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Alternative Name: NR4A1

Background: NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis.
Alias Symbols: GFRP1, HMR, MGC9485, N10, NAK-1, NGFIB, NP10, NUR77, TR3
Protein Interaction Partner: KRTAP10-5, KRTAP10-1, LONRF1, PGBD1, BCL2L10, CDKN2D, BCL2A1, BCL2, TUBB4A, VASP, ANKIB1, CUTA, NFKB1, SMAD3, LSS, HADHA, GLUD1, GK, CPT1A, SERPING1, ABCC6, ABCC13, SOCS4, ABCG8, DIABLO, HCVgp1, ABCA5, CHEK2, SUGT1, PRDX4, PRDX6, CHD1L, ABCB11, ARHGEF5, U
Protein Size: 598

Molecular Weight: 64 kDa

Gene ID: 3164

NCBI Accession: NM_002135, NP_002126

UniProt: P22736

Pathways: Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Steroid Hormone Mediated Signaling Pathway