NOTO antibody (N-Term)

Catalog No. ABIN2779813

The Rabbit Polyclonal anti-NOTO antibody has been validated for WB. It is suitable to detect NOTO in samples from Mouse, Human, Cow, Rat, Dog, Guinea Pig and Rabbit.

Quick Overview for NOTO antibody (N-Term) (ABIN2779813)

Target: NOTO (Notochord Homeobox (NOTO))

Reactivity: Mouse, Human, Cow, Rat, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOTO antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NOTO Antibody

Binding Specificity: N-Term

Sequence: VQPGSLRPCP GAVSPVVPRR LARGRLESSF SVEAILARPK TRELAATSLP

Predicted Reactivity: Cow: 86%, Dog: 85%, Guinea Pig: 93%, Human: 93%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Noto. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of mouse Noto

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 240 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NOTO

Target: NOTO (Notochord Homeobox (NOTO))

Alternative Name: Noto

Background: Noto is a transcription regulator acting downstream of both FOXA2 and T during notochord development.Noto is required for node morphogenesis.Noto is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning, acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate.
Alias Symbols: Flh, MmNot, Not, tc
Protein Size: 240

Molecular Weight: 26 kDa

Gene ID: 384452

NCBI Accession: NM_001007472, NP_001007473

UniProt: A8MTQ0