HHEX antibody (C-Term)

Catalog No. ABIN2779849

The Rabbit Polyclonal anti-HHEX antibody has been validated for WB. It is suitable to detect HHEX in samples from Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse and Rabbit.

Quick Overview for HHEX antibody (C-Term) (ABIN2779849)

Target: HHEX (Hematopoietically Expressed Homeobox (HHEX))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HHEX antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HHEX Antibody

Binding Specificity: C-Term

Sequence: SLDTSCEQGQ DLPSEQNKGA SLDRSQCSPS PASQEDPDSE ISEDSDQEVD

Predicted Reactivity: Cow: 85%, Dog: 86%, Guinea Pig: 92%, Horse: 85%, Human: 86%, Mouse: 100%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against Hhex. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the c terminal region of mouse Hhex

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 271 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HHEX

Target: HHEX (Hematopoietically Expressed Homeobox (HHEX))

Alternative Name: Hhex

Background: Hhex recognizes the DNA sequence 5'-ATTAA-3'. Hhex is a transcriptional repressor.It may play a role in hematopoietic differentiation.Hhex establishes anterior identity at two levels, acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.
Alias Symbols: Hex, Hhex-rs2, Prh, Prhx
Protein Interaction Partner: Sox10, Sox8, SRY, Sp7, Gtf2a1l, Jun, Fos,
Protein Size: 271

Molecular Weight: 30 kDa

Gene ID: 15242

NCBI Accession: NM_008245, NP_032271

UniProt: P43120