NPAS2 antibody (C-Term)

Catalog No. ABIN2779882

The Rabbit Polyclonal anti-NPAS2 antibody has been validated for WB. It is suitable to detect NPAS2 in samples from Mouse and Rat.

Quick Overview for NPAS2 antibody (C-Term) (ABIN2779882)

Target: NPAS2 (Neuronal PAS Domain Protein 2 (NPAS2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPAS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NPAS2 Antibody

Binding Specificity: C-Term

Sequence: PLQPAQAQQQ PPPYLQAPTS LHSEQPDSLL LSTFSQQPGT LGYAATQSTP

Predicted Reactivity: Mouse: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against Npas2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 816 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPAS2

Target: NPAS2 (Neuronal PAS Domain Protein 2 (NPAS2))

Alternative Name: Npas2

Background: BMAL1-NPAS2 heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins.
Alias Symbols: MGC129355, MOP4, bHLHe9
Protein Size: 816

Molecular Weight: 91 kDa

Gene ID: 18143

NCBI Accession: NM_008719, NP_032745

UniProt: P97460

Pathways: Regulation of Lipid Metabolism by PPARalpha, Photoperiodism