YAF2 antibody (Middle Region)

Catalog No. ABIN2780047

The Rabbit Polyclonal anti-YAF2 antibody is suitable to detect YAF2 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig and Horse. It has been validated for WB.

Quick Overview for YAF2 antibody (Middle Region) (ABIN2780047)

Target: YAF2 (YY1 Associated Factor 2 (YAF2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YAF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-YAF2 Antibody

Binding Specificity: Middle Region

Sequence: GDLTVIITDF KEKAKSAPAS SAAGDQHSQG SCSSDSTERG VSRSSSPRGE

Predicted Reactivity: Cow: 80%, Dog: 80%, Guinea Pig: 80%, Horse: 80%, Human: 80%, Mouse: 100%, Rat: 80%

Characteristics: This is a rabbit polyclonal antibody against YAF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse YAF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 179 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for YAF2

Target: YAF2 (YY1 Associated Factor 2 (YAF2))

Alternative Name: YAF2

Background: Yaf2 binds to MYC and inhibits MYC-mediated transactivation. Yaf2 also binds to MYCN and enhances MYCN-dependent transcriptional activation. Yaf2 increases calpain 2-mediated proteolysis of YY1 in vitro. Yaf2 is a component of the E2F6.com-1 complex, a repressive complex that methylates Lys-9 of histone H3, suggesting that it is involved in chromatin-remodeling.
Alias Symbols: 2810021M11Rik
Protein Interaction Partner: Map3k1, Kdm2b, Rnf2,
Protein Size: 179

Molecular Weight: 20 kDa

Gene ID: 67057

NCBI Accession: NM_024189, NP_077151

UniProt: Q99LW6