SP110 antibody (Middle Region)

Catalog No. ABIN2780261

This anti-SP110 antibody is a Rabbit Polyclonal antibody detecting SP110 in WB. Suitable for Human and Horse.

Quick Overview for SP110 antibody (Middle Region) (ABIN2780261)

Target: SP110 (SP110 Nuclear Body Protein (SP110))

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SP110 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SP110 Antibody

Binding Specificity: Middle Region

Sequence: LKAYCHPQSS FFTGIPFNIR DYGEPFQEAM WLDLVKERLI TEMYTVAWFV

Predicted Reactivity: Horse: 75%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SP110. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SP110

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 713 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SP110

Target: SP110 (SP110 Nuclear Body Protein (SP110))

Alternative Name: SP110

Background: The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. SP110 is a member of the SP100/SP140 family of nuclear body proteins and is a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.
Alias Symbols: FLJ22835, IFI41, IFI75, VODI, IPR1
Protein Interaction Partner: UBC, CEBPA, OSGEP, TSC22D1, TTR, TK1, SMN1, CDKN1A, ANXA7, ZSCAN9, NAP1L2, RUNX3, NDUFV2,
Protein Size: 713

Molecular Weight: 81 kDa

Gene ID: 3431

NCBI Accession: NM_080424, NP_536349