RFX2 antibody (Middle Region)

Catalog No. ABIN2780348

This Rabbit Polyclonal antibody specifically detects RFX2 in WB. It exhibits reactivity toward Human.

Quick Overview for RFX2 antibody (Middle Region) (ABIN2780348)

Target: RFX2 (Regulatory Factor X 2 (RFX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RFX2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RFX2 Antibody

Binding Specificity: Middle Region

Sequence: NDLASLSLTL LDKDDMGDEQ RGSEAGPDAR SLGEPLVKRE RSDPNHSLQG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against RFX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RFX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 723 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RFX2

Target: RFX2 (Regulatory Factor X 2 (RFX2))

Alternative Name: RFX2

Background: RFX2 is a member of transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX2 is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene.This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites.
Alias Symbols: FLJ14226
Protein Interaction Partner: RFX6, MDFI, RFX4, RFX1, RFX2,
Protein Size: 723

Molecular Weight: 80 kDa

Gene ID: 5990

NCBI Accession: NM_000635, NP_000626

UniProt: P48378