LMX1B antibody (C-Term)
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- Target See all LMX1B Antibodies
- LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Horse, Zebrafish (Danio rerio), Guinea Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LMX1B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QSPYGSSDPF QQGLTPPQMP GNDSIFHDID SDTSLTSLSD CFLGSSDVGS
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against LMX1B. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human LMX1B
- Top Product
- Discover our top product LMX1B Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 372 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))
- Alternative Name
- LMX1B (LMX1B Products)
- Background
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LMX1B is essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. Defects in LMX1B are the cause of nail-patella syndrome (NPS) also knowan as Onychoosteodysplasia.
Alias Symbols: NPS1, LMX1.2
Protein Interaction Partner: LDB1, APP, SSBP3, TCF3,
Protein Size: 372 - Molecular Weight
- 42 kDa
- Gene ID
- 4010
- NCBI Accession
- NM_002316, NP_002307
- UniProt
- Q6ISC9
- Pathways
- Dopaminergic Neurogenesis
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