MXD1 antibody (N-Term)

Catalog No. ABIN2780418

This Rabbit Polyclonal antibody specifically detects MXD1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Dog, Horse, Zebrafish (Danio rerio) and Sheep.

Quick Overview for MXD1 antibody (N-Term) (ABIN2780418)

Target: MXD1 (MAX Dimerization Protein 1 (MXD1))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Dog, Horse, Zebrafish (Danio rerio), Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MXD1 Antibody

Binding Specificity: N-Term

Sequence: MAAAVRMNIQ MLLEAADYLE RREREAEHGY ASMLPYNNKD RDALKRRNKS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MXD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MXD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 221 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MXD1

Target: MXD1 (MAX Dimerization Protein 1 (MXD1))

Alternative Name: MXD1

Background: MAX dimerization protein belongs to a subfamily of MAX-interacting proteins. MXD1 competes with MYC for binding to MAX to form a sequence-specific DNA-binding complex, acts as a transcriptional repressor (while MYC appears to function as an activator) and is a candidate tumor suppressor.MAX dimerization protein belongs to a subfamily of MAX-interacting proteins. This protein competes with MYC for binding to MAX to form a sequence-specific DNA-binding complex, acts as a transcriptional repressor (while MYC appears to function as an activator) and is a candidate tumor suppressor. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MAD, MAD1, MGC104659, BHLHC58
Protein Interaction Partner: HDAC2, MAX, VDR, APP, BIRC2, RPS6KB1, RPS6KA1, AKT1, SIN3A, KDM5A, SIN3B, PRAM1, SMC3, SAP30, MXD1, MYC, CD2, MYCL, MYCN, PML, MLX, HDAC1,
Protein Size: 221

Molecular Weight: 25 kDa

Gene ID: 4084

NCBI Accession: NM_002357, NP_002348

UniProt: Q0VFI9