IRF4 is a transcriptional activator. It binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter.It also binds the immunoglobulin lambda light chain enhancer, together with PU.1. IRF4 probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.
Alias Symbols: LSIRF, MUM1, NF-EM5
Protein Interaction Partner: UBC, STAT6, BCL6, TOP1, IRAK1, PRRC2B, YTHDC2, VPS35, PEG10, TLK2, CARM1, IKBKAP, ETV7, BATF, HOXB13, PROX1, HOXC11, FKBP4, SPIB, PRDM1, MYD88, TRAF2, NFATC2, SPI1,
Protein Size: 451