PLAG1 antibody (N-Term)

Catalog No. ABIN2780443

The Rabbit Polyclonal anti-PLAG1 antibody has been validated for WB. It is suitable to detect PLAG1 in samples from Human, Mouse, Rat, Guinea Pig, Rabbit, Dog, Horse and Cow.

Quick Overview for PLAG1 antibody (N-Term) (ABIN2780443)

Target: PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Dog, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLAG1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLAG1 Antibody

Binding Specificity: N-Term

Sequence: MATVIPGDLS EVRDTQKVPS GKRKRGETKP RKNFPCQLCD KAFNSVEKLK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PLAG1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PLAG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 500 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLAG1

Target: PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

Alternative Name: PLAG1

Background: PLAG1 is a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas.Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: PSA, SGPA, ZNF912
Protein Interaction Partner: SMAD3, ALB, PIAS4, PIAS2, PIAS1, SUMO1, KPNA2,
Protein Size: 500

Molecular Weight: 56 kDa

Gene ID: 5324

NCBI Accession: NM_002655, NP_002646

UniProt: Q6DJT9