Recoverin antibody (C-Term)

Catalog No. ABIN2780450

The Rabbit Polyclonal anti-Recoverin antibody is suitable to detect Recoverin in samples from Human, Rat, Cow, Dog, Horse, Pig and Rabbit. It has been validated for WB.

Quick Overview for Recoverin antibody (C-Term) (ABIN2780450)

Target: Recoverin (RCVRN)

Reactivity: Human, Rat, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Recoverin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Recoverin Antibody

Binding Specificity: C-Term

Sequence: KMITPEDVKL LPDDENTPEK RAEKIWKYFG KNDDDKLTEK EFIEGTLANK

Predicted Reactivity: Cow: 86%, Dog: 79%, Horse: 86%, Human: 100%, Pig: 75%, Rabbit: 79%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against RCV1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RCV1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 200 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Recoverin

Target: Recoverin (RCVRN)

Alternative Name: RCV1

Background: RCV1 is a member of the recoverin family of neuronal calcium sensors. RCV1 contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.The protein encoded by this gene contains four calcium-binding EF-hand domains and belongs to the recoverin family of neuronal calcium sensors. Recoverin may prolong the termination of the phototransduction cascade by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy, an autoimmune disease of the retina caused by a tumor in another tissue.
Alias Symbols: RCV1, RCVRN
Protein Interaction Partner: GIT2, TGFBR2, SMAD3, IL15RA, TOP1, PQBP1, CAV1, GRK5, GRK6, GRK1, ADRBK1,
Protein Size: 200

Molecular Weight: 23 kDa

Gene ID: 5957

NCBI Accession: NM_002903, NP_002894

UniProt: Q53XL0

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction