TEAD4 antibody (C-Term)

Catalog No. ABIN2780491

This Rabbit Polyclonal antibody specifically detects TEAD4 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog and Zebrafish (Danio rerio)and has been mentioned in 1 publication.

Quick Overview for TEAD4 antibody (C-Term) (ABIN2780491)

Target: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TEAD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TEAD4 Antibody

Binding Specificity: C-Term

Sequence: MMNSVLENFT ILQVVTNRDT QETLLCIAYV FEVSASEHGA QHHIYRLVKE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against TEAD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TEAD4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 434 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TEAD4 antibody (ABIN2780491)

Ribas, Moncaut, Siligan, Taylor, Cross, Rigby, Carvajal: "Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments." in: Developmental biology, Vol. 355, Issue 2, pp. 372-80, (2011) (PubMed).

Target Details for TEAD4

Target: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Alternative Name: TEAD4

Background: TEAD4 is a member of the transcriptional enhancer factor (TEF) family. The family members contain the TEA/ATTS DNA-binding domain. TEAD4 is preferentially expressed in skeletal muscle, and binds to the M-CAT regulatory element which directs muscle-specific gene expression. TEAD4 is encoded through the use of a non-AUG (TTG) translation initiation codon. This gene encodes a member of the transcriptional enhancer factor (TEF) family. The family members contain the TEA/ATTS DNA-binding domain. This member is preferentially expressed in skeletal muscle, and binds to the M-CAT regulatory element which directs muscle-specific gene expression. The protein is encoded through the use of a non-AUG (TTG) translation initiation codon. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: TEF3, RTEF1, TEF-3, EFTR-2, TEFR-1, TCF13L1, hRTEF-1B
Protein Interaction Partner: CCDC172, SSX2IP, LZTS2, CEP70, CEP55, RABGEF1, CCNDBP1, KIAA0753, PNMA1, TRAF1, VPS52, TRIM27, GOLGA2, UBC, SUMO2, CCDC85B, WWTR1, YAP1, VGLL1, MYH7,
Protein Size: 434

Molecular Weight: 48 kDa

Gene ID: 7004

NCBI Accession: NM_003213, NP_003204

UniProt: Q96BK2

Pathways: Regulation of Lipid Metabolism by PPARalpha