KLF11 antibody (C-Term)

Catalog No. ABIN2780537

This Rabbit Polyclonal antibody specifically detects KLF11 in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig and Zebrafish (Danio rerio)and has been mentioned in 1 publication.

Quick Overview for KLF11 antibody (C-Term) (ABIN2780537)

Target: KLF11 (Kruppel-Like Factor 11 (KLF11))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KLF11 Antibody

Binding Specificity: C-Term

Sequence: KFARSDELSR HRRTHTGEKK FVCPVCDRRF MRSDHLTKHA RRHMTTKKIP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against KLF11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KLF11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 512 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-KLF11 antibody (ABIN2780537)

Duncan, Wang, Zhang, Johnson, Harris, Zheng, Zhang, Rajkowska, Miguel-Hidalgo, Sittman, Ou, Stockmeier, Wang: "Chronic Social Stress and Ethanol Increase Expression of KLF11, a Cell Death Mediator, in Rat Brain." in: Neurotoxicity research, Vol. 28, Issue 1, pp. 18-31, (2015) (PubMed).

Target Details for KLF11

Target: KLF11 (Kruppel-Like Factor 11 (KLF11))

Alternative Name: KLF11

Background: KLF11 (TIEG2) is a pancreas-enriched transcription factor that has elicited significant attention because of its role as negative regulator of exocrine cell growth in vitro and in vivo. It plays a role in the regulation of pancreatic beta cell physiology, and its variants may contribute to the development of diabetes.
Alias Symbols: FKLF, FKLF1, MODY7, TIEG2, Tieg3
Protein Interaction Partner: APPBP2, TXNDC9, APH1A, TIMM13, YWHAZ, CLU, SIN3A, MAPK1, ATXN1, CBX5, CBX3, CBX1, EP300, ELAVL1, UBC, HDAC1,
Protein Size: 512

Molecular Weight: 55 kDa

Gene ID: 8462

NCBI Accession: NM_003597, NP_003588

UniProt: O14901