Deltex Homolog 1 antibody (N-Term)

Catalog No. ABIN2780591

Product Details anti-Deltex Homolog 1 Antibody

Target: Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Deltex Homolog 1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SRWRPYTATV CHHIENVLKE DARGSVVLGQ VDAQLVPYII DLQSMHQFRQ

Predicted Reactivity: Cow: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DTX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DTX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 620 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Deltex Homolog 1

Target: Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))

Alternative Name: DTX1 (DTX1 Products)

Background: Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function, however, it may play a role in basic helix-loop-helix transcription factor activity.
Alias Symbols: hDx-1
Protein Interaction Partner: TAX1BP3, G3BP1, DEFA5, EGR2, UBC, ITCH, EIF3F, NOTCH1, MAP3K1, UBE2U, UBE2D4, UBE2C, UBE2N, UBE2E1, UBE2D3, UBE2D2, UBE2D1, DTX3L, DTX3, DTX2, EP300, DTX1, NOTCH2, GRB2,
Protein Size: 620

Molecular Weight: 67 kDa

Gene ID: 1840

NCBI Accession: NM_004416, NP_004407

UniProt: Q86Y01

Pathways: Notch Signaling