CIAO1 antibody (N-Term)

Catalog No. ABIN2780620

This Rabbit Polyclonal antibody specifically detects CIAO1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for CIAO1 antibody (N-Term) (ABIN2780620)

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIAO1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CIAO1 Antibody

Binding Specificity: N-Term

Sequence: MKDSLVLQSR VPAHPDSRCW FLAWNPSGTL LASCGGDRKI RIWGTEGDSW

Predicted Reactivity: Cow: 79%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Ciao1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Ciao1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 339 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CIAO1

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Alternative Name: Ciao1

Background: Ciao1 is an essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. It is required for the maturation of extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
Alias Symbols: AW210570, Wdr39
Protein Interaction Partner: Iqcb1,
Protein Size: 339

Molecular Weight: 38 kDa

Gene ID: 26371

NCBI Accession: NM_025296, NP_079572

UniProt: Q99KN2