ARID3A antibody (N-Term)

Catalog No. ABIN2780661

This Rabbit Polyclonal antibody specifically detects ARID3A in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig and Goatand has been mentioned in 1 publication.

Quick Overview for ARID3A antibody (N-Term) (ABIN2780661)

Target: ARID3A (AT Rich Interactive Domain 3A (BRIGHT-Like) (ARID3A))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARID3A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARID3A Antibody

Binding Specificity: N-Term

Sequence: MKLQAVMETL LQRQQRARQE LEARQQLPPD PPAAPPGRAR AAPDEDREPE

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 83%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ARID3A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ARID3A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 593 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ARID3A antibody (ABIN2780661)

Lin, Ippolito, Zong, Bryant, Koslovsky, Tucker: "Bright/ARID3A contributes to chromatin accessibility of the immunoglobulin heavy chain enhancer." in: Molecular cancer, Vol. 6, pp. 23, (2007) (PubMed).

Target Details for ARID3A

Target: ARID3A (AT Rich Interactive Domain 3A (BRIGHT-Like) (ARID3A))

Alternative Name: ARID3A

Background: ARID3A is a member of the ARID (AT-rich interaction domain) family of proteins which bind DNA. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification.This gene is a member of the ARID (AT-rich interaction domain) family of proteins which bind DNA. It was found by its homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-396 BC060828.1 1-396 397-2254 U88047.1 307-2164 2255-2766 CR598405.1 1491-2002 2767-2823 BC060828.1 2769-2825
Alias Symbols: BRIGHT, DRIL1, DRIL3, E2FBP1
Protein Interaction Partner: NOTCH2NL, TTC32, UBC, SOX2, TP53BP1, APP, UBE2E3, TP53, SP100, PML, E2F4, E2F2, RL2, ELAVL1, SUMO2, BTK, E2F1, DSP,
Protein Size: 593

Molecular Weight: 63 kDa

Gene ID: 1820

NCBI Accession: NM_005224, NP_005215

UniProt: Q99856

Pathways: Chromatin Binding