HCFC1 antibody (N-Term)

Catalog No. ABIN2780670

The Rabbit Polyclonal anti-HCFC1 antibody has been validated for WB. It is suitable to detect HCFC1 in samples from Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Zebrafish (Danio rerio) and Guinea Pig.

Quick Overview for HCFC1 antibody (N-Term) (ABIN2780670)

Target: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCFC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HCFC1 Antibody

Binding Specificity: N-Term

Sequence: GTRLLVFGGM VEYGKYSNDL YELQASRWEW KRLKAKTPKN GPPPCPRLGH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against HCFC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HCFC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 428 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HCFC1

Target: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Alternative Name: HCFC1

Background: HCFC1 is a member of the host cell factor family with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection.
Alias Symbols: CFF, HCF1, HFC1, VCAF, HCF-1
Protein Interaction Partner: FBXW11, BAP1, NUDCD3, CREB3, UBC, RPA3, RPA2, RPA1, EED, EEF1D, CREBZF, LMNA, OGT, POU2F1, NOTCH1, UL48, RBBP5, PPP1CB, PPP1CA, DPY30, WDR5, MAP3K7, HCFC1, EGFR, CLP1, YEATS2, CDK2, CUL3, USF1, NR2C1, THAP11, SIRT7, ELAVL1, SUMO2, ASH2L, SNRPN, SNRPB, YY1
Protein Size: 428

Molecular Weight: 45 kDa

Gene ID: 3054

NCBI Accession: NM_005334