MYB antibody (C-Term)

Catalog No. ABIN2780680

This anti-MYB antibody is a Rabbit Polyclonal antibody detecting MYB in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit and Guinea Pig.

Quick Overview for MYB antibody (C-Term) (ABIN2780680)

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MYB Antibody

Binding Specificity: C-Term

Sequence: AFTVPKNRSL ASPLQPCSST WEPASCGKME EQMTSSSQAR KYVNAFSART

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against MYB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MYB

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYB

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Alternative Name: MYB

Background: This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.
Protein Interaction Partner: UBC, ERC2, UPF2, PPM1K, MYOZ2, SUMO1, SUMO2, CCND3, EP300, RBX1, FBXW5, PIAS1, CUL4A, UBE2I, DDB1, TRAF6, STAT5A, GATA3, KAT5, Fbxw7, CREBBP, LEF1, RPL4, KAT2B, CHD3, SIN3A, TRIM28, NCOR1, SKI, HIPK2, NLK, SP100, HLF, PARP1, ASH2L, RBBP5, KMT2A, MEN1, WDR
Protein Size: 555

Molecular Weight: 61 kDa

Gene ID: 4602

Pathways: Chromatin Binding, Positive Regulation of Immune Effector Process