MEF2D antibody (Middle Region)

Catalog No. ABIN2780725

The Rabbit Polyclonal anti-MEF2D antibody has been validated for WB. It is suitable to detect MEF2D in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for MEF2D antibody (Middle Region) (ABIN2780725)

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2D antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MEF2D Antibody

Binding Specificity: Middle Region

Sequence: GDGLSSPAGG SYETGDRDDG RGDFGPTLGL LRPAPEPEAE GSAVKRMRLD

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MEF2D. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MEF2D

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 521 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MEF2D

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Alternative Name: MEF2D

Background: MEF2D is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. MEF2D mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival.MEF2D plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription.MEF2D plays a critical role in the regulation of neuronal apoptosis.
Alias Symbols: DKFZp686I1536
Protein Interaction Partner: SUMO1, CDK6, ASCL1, APP, SUMO2, UBC, CABIN1, MEF2A, HDAC1, HIRA, ASH2L, KMT2D, RBBP5, MEN1, PRKACA, SENP3, HDAC4, COPS5, CARM1, PRMT5, KAT2B, HDAC3, SNCA, MAPK14, HDAC5, EP300, MAPK7, CASP7, MEF2D, MEF2C, NFATC2, SP1, YWHAQ,
Protein Size: 521

Molecular Weight: 56 kDa

Gene ID: 4209

NCBI Accession: NM_005920, NP_005911

UniProt: Q14814