NAB2 antibody (C-Term)

Catalog No. ABIN2780731

The Rabbit Polyclonal anti-NAB2 antibody has been validated for WB. It is suitable to detect NAB2 in samples from Human, Mouse, Rat, Cow, Dog, Rabbit, Horse and Guinea Pig.

Quick Overview for NAB2 antibody (C-Term) (ABIN2780731)

Target: NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NAB2 Antibody

Binding Specificity: C-Term

Sequence: GRLSPCVPAK PPLAEFEEGL LDRCPAPGPH PALVEGRRSS VKVEAEASRQ

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NAB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NAB2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 525 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NAB2

Target: NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))

Alternative Name: NAB2

Background: NAB2 is a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize withThis gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MADER, MGC75085
Protein Interaction Partner: AES, KRT40, ZMYND19, TGIF2LY, TCHP, CCDC33, GCC1, LENG1, SCNM1, ZBED8, TTC19, CCHCR1, NME7, RBPMS, MORF4L1, JAKMIP2, RFC5, PIN1, PHF1, NEDD9, NAB2, MDFI, MCM7, PHOSPHO2, SUMO1P1, NOTCH2NL, KRTAP10-3, KRTAP10-8, TCEANC, CWF19L2, DGCR6, MAPK3, VBP1, TLN1, S
Protein Size: 525

Molecular Weight: 56 kDa

Gene ID: 4665

NCBI Accession: NM_005967, NP_005958

UniProt: Q15742