ZBTB16 antibody (C-Term)

Catalog No. ABIN2780737

The Rabbit Polyclonal anti-ZBTB16 antibody has been validated for WB. It is suitable to detect ZBTB16 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) and Goat. There is 1 publication available.

Quick Overview for ZBTB16 antibody (C-Term) (ABIN2780737)

Target: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB16 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZBTB16 Antibody

Binding Specificity: C-Term

Sequence: GASPYQCTIC TEYCPSLSSM QKHMKGHKPE EIPPDWRIEK TYLYLCYV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ZBTB16. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ZBTB16

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 673 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ZBTB16 antibody (ABIN2780737)

Deng, Zhang, Kang, Liu, Zhao, Gao, Li, Pan, Tang, Wang, Niu, Yang, Zeng: "An unusual haplotype structure on human chromosome 8p23 derived from the inversion polymorphism." in: Human mutation, Vol. 29, Issue 10, pp. 1209-16, (2008) (PubMed).

Target Details for ZBTB16

Target: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Alternative Name: ZBTB16

Background: ZBTB16 is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.
Alias Symbols: PLZF, ZNF145
Protein Interaction Partner: KRT40, SH2D4A, TRIM54, LAMTOR5, IL32, ZBTB16, SUMO2, PRKCE, GOLGA2, HDAC1, CEBPA, EP300, MBD3, SIN3A, CBX5, NCOR1, MTA2, HDAC3, TP53, NCOR2, ZNF281, TAB2, SMAD3, CFH, ADAMTS4, HOXA1, CASP3, ATP7B, PARP1, TIMP1, FSHR, EEF1A1, TNK2, ATP6AP2, HDAC4, Gne, Gna
Protein Size: 673

Molecular Weight: 74 kDa

Gene ID: 7704

NCBI Accession: NM_006006, NP_005997

UniProt: Q05516

Pathways: Positive Regulation of fat Cell Differentiation