PDLIM5 antibody (N-Term)

Catalog No. ABIN2780775

This anti-PDLIM5 antibody is a Rabbit Polyclonal antibody detecting PDLIM5 in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Horse, Rabbit and Guinea Pig.

Quick Overview for PDLIM5 antibody (N-Term) (ABIN2780775)

Target: PDLIM5 (PDZ and LIM Domain 5 (PDLIM5))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDLIM5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDLIM5 Antibody

Binding Specificity: N-Term

Sequence: SNYSVSLVGP APWGFRLQGG KDFNMPLTIS SLKDGGKAAQ ANVRIGDVVL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against PDLIM5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PDLIM5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 596 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDLIM5

Target: PDLIM5 (PDZ and LIM Domain 5 (PDLIM5))

Alternative Name: PDLIM5

Background: PDLIM5 is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized. The protein encoded by this gene is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized.
Alias Symbols: ENH, ENH1, L9, LIM
Protein Interaction Partner: KRTAP10-7, KRT40, CCDC136, COIL, ZYX, UBC, SUMO2, SUMO3, SUZ12, RNF2, BMI1, PDE12, NPLOC4, IPO11, PLIN3, UBA2, EIF4A3, ANP32A, TPD52, SRP14, RAD23B, PKM, METTL1, CBS, CALU, FN1, ELMSAN1, SIN3A, DSTN, NDUFA7, GFI1B, SUMO1, TRIM39, CACNA1B, PRKCG, PRKCE, PR
Protein Size: 596

Molecular Weight: 64 kDa

Gene ID: 10611

NCBI Accession: NM_006457, NP_006448

UniProt: Q96HC4