TCERG1 antibody (N-Term)
Quick Overview for TCERG1 antibody (N-Term) (ABIN2780799)
Target
See all TCERG1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- AERGGDGGES ERFNPGELRM AQQQALRFRG PAPPPNAVMR GPPPLMRPPP
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Predicted Reactivity
- Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 86%, Rat: 93%
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Characteristics
- This is a rabbit polyclonal antibody against TCERG1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TCERG1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 1098 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TCERG1 (Transcription Elongation Regulator 1 (TCERG1))
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Alternative Name
- TCERG1
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Background
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TCERG1 is a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. TCERG1 interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.
Alias Symbols: CA150, MGC133200, TAF2S, Urn1
Protein Interaction Partner: CEP76, UBC, RPA3, RPA2, RPA1, EED, WIPF2, PSPC1, WWOX, EVL, CYFIP2, BRD4, SF3B1, SF3B3, CYFIP1, U2AF2, WBP4, CPSF6, NUDT21, SF3B2, SF3A3, DIAPH2, DIAPH1, FMNL1, SF3A1, WASF2, ABI1, SF3A2, SF1, WAS, SFPQ, NONO, HNRNPU, HNRNPK, JUNB, FN1, Dlg4, ITGA4, PSAP,
Protein Size: 1098 -
Molecular Weight
- 124 kDa
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Gene ID
- 10915
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NCBI Accession
- NM_006706, NP_006697
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UniProt
- O14776
Target
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