HEY2 antibody (Middle Region)

Catalog No. ABIN2780874

Product Details anti-HEY2 Antibody

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Guinea Pig, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEY2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PMLPPNAAAA VAAATAISPP LSVSATSSPQ QTSSGTNNKP YRPWGTEVGA

Predicted Reactivity: Cow: 93%, Dog: 90%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 90%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against HEY2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HEY2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 337 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HEY2

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Alternative Name: HEY2 (HEY2 Products)

Background: HEY2 is a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. HEY2 forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repres
Alias Symbols: CHF1, GRL, HERP1, HESR2, HRT2, MGC10720, bHLHb32, GRIDLOCK
Protein Interaction Partner: RBPMS, TRAF1, SYVN1, DERL2, HEY1, SEL1L, HTT, ATXN1, ARNT, NOTCH1, BTRC, CASP3, SIN3A, PLSCR1, SIRT1, HEY2, HAND2, HAND1, HDAC1, NCOR1, HES1, HDAC9,
Protein Size: 337

Molecular Weight: 36 kDa

Gene ID: 23493

NCBI Accession: NM_012259, NP_036391

UniProt: Q9UBP5

Pathways: Regulation of Muscle Cell Differentiation