HEY2 antibody (Middle Region)

Catalog No. ABIN2780874

The Rabbit Polyclonal anti-HEY2 antibody has been validated for WB. It is suitable to detect HEY2 in samples from Human, Mouse, Rat, Zebrafish (Danio rerio), Guinea Pig, Cow, Dog, Horse and Rabbit.

Quick Overview for HEY2 antibody (Middle Region) (ABIN2780874)

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Guinea Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEY2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HEY2 Antibody

Binding Specificity: Middle Region

Sequence: PMLPPNAAAA VAAATAISPP LSVSATSSPQ QTSSGTNNKP YRPWGTEVGA

Predicted Reactivity: Cow: 93%, Dog: 90%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 90%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against HEY2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HEY2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 337 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HEY2

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Alternative Name: HEY2

Background: HEY2 is a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. HEY2 forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repres
Alias Symbols: CHF1, GRL, HERP1, HESR2, HRT2, MGC10720, bHLHb32, GRIDLOCK
Protein Interaction Partner: RBPMS, TRAF1, SYVN1, DERL2, HEY1, SEL1L, HTT, ATXN1, ARNT, NOTCH1, BTRC, CASP3, SIN3A, PLSCR1, SIRT1, HEY2, HAND2, HAND1, HDAC1, NCOR1, HES1, HDAC9,
Protein Size: 337

Molecular Weight: 36 kDa

Gene ID: 23493

NCBI Accession: NM_012259, NP_036391

UniProt: Q9UBP5

Pathways: Regulation of Muscle Cell Differentiation