TRIM35 antibody (C-Term)

Catalog No. ABIN2780959

This Rabbit Polyclonal antibody specifically detects TRIM35 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog and Saccharomyces cerevisiae.

Quick Overview for TRIM35 antibody (C-Term) (ABIN2780959)

Target: TRIM35 (Tripartite Motif Containing 35 (TRIM35))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM35 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM35 Antibody

Binding Specificity: C-Term

Sequence: RTQGVEGDHC VTSDPATSPL VLAIPRRLRV ELECEEGELS FYDAERHCHL

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Yeast: 85%

Characteristics: This is a rabbit polyclonal antibody against TRIM35. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TRIM35

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 493 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM35

Target: TRIM35 (Tripartite Motif Containing 35 (TRIM35))

Alternative Name: TRIM35

Background: TRIM35 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM35 may play a role as a tumor suppressor, and is implicated in the cell death mechanism
Protein Interaction Partner: USP49, PAN2, USP2, TRIM5, TRIM11, UBE2U, UBE2W, UBE2D4, UBE2D3, UBE2D2, UBE2D1, TSG101, UBE2K,
Protein Size: 493

Molecular Weight: 57 kDa

Gene ID: 23087

NCBI Accession: NM_015066, NP_055881

UniProt: Q9UPQ4