NKRF antibody (Middle Region)

Catalog No. ABIN2781032

This Rabbit Polyclonal antibody specifically detects NKRF in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Rabbit, Cow and Guinea Pig.

Quick Overview for NKRF antibody (Middle Region) (ABIN2781032)

Target: NKRF (NFKB Repressing Factor (NKRF))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKRF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NKRF Antibody

Binding Specificity: Middle Region

Sequence: QKYGLKSKSH GVGHDRYLVV GRKRRKEDLL DQLKQEGQVG HYELVMPQAN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NKRF. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NKRF

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 690 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NKRF

Target: NKRF (NFKB Repressing Factor (NKRF))

Alternative Name: NKRF

Background: NKRF is a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. NKRF localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.This gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. This gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.
Alias Symbols: ITBA4, NRF
Protein Interaction Partner: STAU1, UBC, XRN2, BMI1, TARDBP, BARD1, CAND1, COPS5, CUL1, CUL3, SIRT7, HNRNPA1, SUMO2, VHL, DHX58, PRKRA, SUMO1, HMOX2, BCL6, REL, RELA, NFKB2, NFKB1,
Protein Size: 690

Molecular Weight: 78 kDa

Gene ID: 55922

NCBI Accession: NM_017544, NP_060014

UniProt: O15226