ARNTL2 antibody (N-Term)

Catalog No. ABIN2781092

The Rabbit Polyclonal anti-ARNTL2 antibody has been validated for WB and IHC. It is suitable to detect ARNTL2 in samples from Human, Mouse and Dog.

Quick Overview for ARNTL2 antibody (N-Term) (ABIN2781092)

Target: ARNTL2 (Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2))

Reactivity: Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARNTL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ARNTL2 Antibody

Binding Specificity: N-Term

Sequence: PTAMGSFSSH MTEFPRKRKG SDSDPSQSGI MTEKVVEKLS QNPLTYLLST

Predicted Reactivity: Dog: 86%, Human: 100%, Mouse: 77%

Characteristics: This is a rabbit polyclonal antibody against ARNTL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ARNTL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 636 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARNTL2

Target: ARNTL2 (Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2))

Alternative Name: ARNTL2

Background: ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1.
Alias Symbols: BMAL2, CLIF, MGC149671, MGC149672, MOP9, PASD9, bHLHe6
Protein Interaction Partner: NPAS2, UBC, EPAS1, CLOCK,
Protein Size: 636

Molecular Weight: 71 kDa

Gene ID: 56938

NCBI Accession: NM_020183, NP_064568

UniProt: Q8WYA1

Pathways: Photoperiodism