HOXC8 antibody (N-Term)

Catalog No. ABIN2781186

The Rabbit Polyclonal anti-HOXC8 antibody has been validated for WB and IHC. It is suitable to detect HOXC8 in samples from Human, Mouse, Rat, Sheep, Dog, Cow, Rabbit, Horse and Zebrafish (Danio rerio).

Quick Overview for HOXC8 antibody (N-Term) (ABIN2781186)

Target: HOXC8 (Homeobox C8 (HOXC8))

Reactivity: Human, Mouse, Rat, Sheep, Dog, Cow, Rabbit, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXC8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HOXC8 Antibody

Binding Specificity: N-Term

Sequence: SHALVYGPGG SAPGFQHASH HVQDFFHHGT SGISNSGYQQ NPCSLSCHGD

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against HOXC8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXC8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 242 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HOXC8

Target: HOXC8 (Homeobox C8 (HOXC8))

Alternative Name: HOXC8

Background: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-935 BC053898.1 1-935 936-1866 BC053898.1 937-1867 1867-2290 BU618342.1 3-426 c
Alias Symbols: HOX3, HOX3A
Protein Interaction Partner: UBC, PBX1, HOMEZ, GMNN, SMAD6, BTG2, SMAD1, BMPR1A, SMAD4, JUN, MSX1, DLX5, DLX2, KMT2A,
Protein Size: 242

Molecular Weight: 28 kDa

Gene ID: 3224

NCBI Accession: NM_022658, NP_073149

UniProt: P31273